Power and Pitfalls of the Genome-Wide Association Study ...
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Suicides in Late Life
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Antisynthetase Syndrome
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Treatment of Lupus Nephritis
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The Genetics of Scleroderma
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Treatment of Cutaneous Lupus
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Malignancy in Myositis
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Power and Pitfalls of the Genom ...
Until recently, the search for genes contributing to Alzheimer’s disease (AD) had been slow and disappointing, with the notable exception of the APO ...
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A Tipping Point in Drug Dosing ...
Minimally effective doses of antipsychotics are likely influenced by several clinical and demographic characteristics of patients, with age being on ...
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Update: Schizophrenia Across Cu ...
The incidence of schizophrenia, as well as the symptoms, course, and outcomes for people so diagnosed seem to vary across some cultural contexts. Th ...
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State of the Art in the Pharmac ...
This article reviews the most recent studies of the pharmacologic treatment of borderline personality disorder (BPD). Although research continues us ...
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Genome-Wide Association Studies ...
Genome-wide association studies (GWAS) currently represent the most systematic approach to genetic research into complex disorders. They can detect ...
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Suicides in Late Life
Suicide in late life is an enormous public health problem that will likely increase in severity as adults of the baby boom generation age. Data from ...
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Genetics of Antipsychotic-induc ...
Antipsychotic medication has been enormously helpful in the treatment of psychotic symptoms during the past several decades. Unfortunately, several ...
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New Developments in Brief Inter ...
The delivery of brief interventions (BIs) in health care settings to reduce problematic alcohol consumption is a key preventive strategy for public ...
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Antisynthetase Syndrome
Autoantibodies to eight of the aminoacyltransfer RNA synthetases—the most well-recognized of which is anti-histidyl (Jo-1)—have all been implicated ...
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Treatment of Lupus Nephritis
The treatment of lupus nephritis has evolved over the past few decades. Standard practice is to define the first 6 months of therapy as an induction ...
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Therapeutic Approaches in Myosi ...
The inflammatory myopathies are a heterogeneous group of diseases including dermatomyositis, polymyositis, and inclusion body myositis. Few clinical ...
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Clinical Assessment and Managem ...
Anemia, leukopenia, and/or thrombocytopenia can occur as a result of non-immune- and immunemediated mechanisms in patients with systemic lupus eryt ...
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Biomarkers in the Management of ...
Scleroderma, or systemic sclerosis, is a clinically heterogeneous disease characterized by fibroproliferative vasculopathy, tissue fibrosis affectin ...
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The Immune System, the Skin, an ...
As the body’s largest organ and first line of defense against the environment, the skin plays a vital role in host immune defense. In addition to it ...
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The Genetics of Scleroderma
The importance of the genetic component in the pathogenesis of scleroderma, or systemic sclerosis, has been strengthened in the past 2 years with st ...
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Mechanisms of Action of Intrave ...
Intravenous immunoglobulin (IVIG) is a unique immune-modulating therapy that has a wide range of effects on the immune system at multiple levels. Th ...
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Treatment of Cutaneous Lupus
Cutaneous lupus erythematosus (CLE) is an autoimmune inflammatory skin disease seen in patients with or without systemic lupus erythematosus. The ma ...
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Vitamin D Supplementation in th ...
Vitamin D is capturing the attention of healthy and chronically ill populations for its potential skeletal and nonskeletal benefits. New information ...
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The Muscular Dystrophies: Disti ...
Over the past decade, the enigmatic pathogenic mechanisms of the most common forms of muscular dystrophy have been defined. In this report, the mole ...
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Tyrosine Kinase Inhibitors in t ...
Efficient antifibrotic therapies are not available for patients with systemic sclerosis (SSc). This review summarizes the current preclinical and cl ...
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Treatment of Mild, Moderate, an ...
Despite large-scale efforts devoted to the conduct of clinical trials in systemic lupus erythematosus (SLE), no new therapy has been approved for tr ...
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Pediatric Rheumatology in South ...
Pediatric rheumatology is a well-established subspecialty in just 4 of 11 Southeast Asia countries. With the development of a dedicated pediatric rh ...
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Malignancy in Myositis
Dermatomyositis is associated with an underlying malignancy in about 24% of cases. This association is also true for polymyositis but is less promin ...
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A Unifying Hypothesis for Scler ...
We propose that a recent change in the conception of the role of type 1 interferon and the identification of adventitial stem cells suggests a unify ...
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To What Extent Can Preventive T ...
Managing lupus patients traditionally involves treating manifestations of active disease with the most effective and least toxic therapies so that “ ...
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