Second-line chemotherapy for ga ...
Chemotherapy for gastric cancer has been advancing fairly well. It has been indicated that not only advances in first-line chemotherapy but also tho ...
Clinical features and predictiv ...
Background Various endoscopic submucosal dissection (ESD)-related complications, such as perforation or bleeding, occur frequently. However, the cli ...
Effective palliation and qualit ...
Background Relief of symptoms should be the primary focus of palliative treatment as defined by the World Health Organization. Evaluating the effect ...
Gastric linitis plastica: which ...
Background The role of surgery for gastric linitis plastica (GLP) is questioned. This study aimed to analyze our experience in the surgical treatmen ...
Usefulness of transnasal endosc ...
Background Early gastric cancer located from the pyloric ring to inside the duodenal bulb (DB) is not easily treated by endoscopic submucosal dissec ...
Safety and feasibility of S-1 a ...
Background The safety and feasibility of administering S-1 adjuvant chemotherapy for gastric cancer has not been fully evaluated in elderly patients ...
Early gastric cancer combined w ...
We report a 75-year-old woman who suffered multiple metachronous osteosclerotic bone metastases 4 years after a distal gastrectomy for early gastric ...
A systematic review of the accu ...
Background Despite improved preoperative imaging techniques, patients with incurable or unresectable gastric cancer are still subjected to non-thera ...
Single-institute prospective tr ...
Background Laparoscopy-assisted gastrectomy (LAG) is an advanced surgery that requires the mastery of complex surgical skills. We evaluate the feasi ...
Phase II trial of combined trea ...
Background To improve the poor prognosis in patients with stage IV (StIV) gastric cancer (GC), we conducted a multicenter phase II study of preopera ...
Multicenter study of the long-t ...
Background Little information is available on the longterm outcomes of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) in pati ...
Frequent development of leptome ...
We detected 7 cases of leptomeningeal carcinomatosis in 126 patients with peritoneal dissemination of gastric cancer who received combined systemic ...
A multiple-center phase II stud ...
Background Docetaxel and oxaliplatin are active agents for advanced gastric cancer (GC). The combination of these two drugs in a triweekly schedule ...
Decreased NKG2D expression on N ...
Background Although malignant diseases are known to be associated with immune suppression, the detailed mechanisms involved are still unknown. NKG2D ...
Clinicopathological analysis fo ...
Background The prognosis for patients with stage Ib (second English edition of the Japanese classification of gastric carcinoma) gastric cancer is p ...
First-line fluorouracil-based c ...
Background Treatment with an oral fluoropyrimidine plus cisplatin is widely used for advanced gastric cancer, but patients with severe peritoneal me ...
The delta-shaped anastomosis in ...
Background We developed a new method of intracorporeal gastroduodenostomy, the delta-shaped anastomosis, in which only endoscopic linear staplers ar ...
Survival benefit of bursectomy ...
Background Bursectomy is regarded as a standard surgical procedure during gastrectomy for serosa-positive gastric cancer in Japan. There is little e ...
Optimal indications of surgical ...
Background Decision-making for surgical palliation remains one of the most challenging clinical scenarios. We investigated the optimal indications f ...
Bacteremia and endotoxemia afte ...
Background Because the invasive procedure of endoscopic submucosal dissection (ESD) entails a large mucosal defect which is left open, with extensiv ...
Evaluation of modified Estimati ...
Background We recently modified our prediction scoring system ‘‘Estimation of Physiologic Ability and Surgical Stress’’ and have designated the curr ...
Value of sentinel lymph node ma ...
Background Forty percent of patients with gastric cancer have unnecessarily extended lymph node dissections with higher rates of morbidity and morta ...
A small interfering RNA targeti ...
Background Accumulating evidence suggests that the tumor suppressor gene Kruppel-like factor 6 (KLF6) and its dominant-negative splice form KLF6-SV1 ...
Functional outcomes according t ...
Background In gastric cancer, various methods of gastric resection and reconstruction have been devised according to the location of the primary tum ...
Human gastrin mRNA expression u ...
Background Helicobacter pylori-cytotoxin-associated protein A (CagA) and gastrin are believed to play an important role in gastric carcinogenesis, b ...