Defining Features and Exploring Chemical Modifications ...
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Foamy Virus Vectors
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Defining Features and Exploring ...
RNA interference (RNAi) is an evolutionary conserved mechanism by which small double-stranded RNA (dsRNA) – termed small interfering RNA (siRNA) – in ...
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Plasmid DNA and viral vector-ba ...
Plasmid DNA and viral vector-based cancer vaccines have many inherent features that make them promising cancer vaccine candidates. This review focuse ...
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From the Obscure and Mysterious ...
The discovery of C-reactive protein (CRP) almost 80 years ago in the blood of patients with various infectious and inflammatory diseases initiated st ...
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Pharmacological Modulation of D ...
Members of the classic type of transient receptor potential channels (TRPC) represent important molecules involved in hormonal signal transduction. T ...
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The Expanding Universe of .. .. ...
.... T cells which express the V..9 and V..2 gene products are unique to primates and represent only a minor population of peripheral blood T lymphoc ...
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IgG4-Related Disease (IgG4+MOLP ...
Since the first report on patients with elevated serum IgG4 in sclerosing pancreatitis in 2001, various systemic disorders, described by many names, ...
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Immunological Aspects of Adult ...
Adult T-cell leukemia/lymphoma (ATLL) is a distinct disease caused by the first discovered human oncogenic retrovirus, human T-cell leukemia virus ty ...
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Immunobiology of Herpes Simplex ...
Immunologic “immaturity” is often blamed for the increased susceptibility of newborn humans to infection, but the precise mechanisms and details of i ...
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Joint Diseases and Matrix Metal ...
The role of matrix metalloproteinases in disease has been investigated over the last two decades. A focus on this family of proteases is particularly ...
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Use of Lactobacilli and their P ...
Lactobacilli are common microorganisms in diverse vegetables and meat products and several of these are also indigenous inhabitants in the gastro-int ...
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Negative Regulation of TCR Sign ...
To prevent the occurrence and expansion of autoreactive T cell clones, and hence the development of autoimmune disease (such as multiple sclerosis, r ...
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Fluorescence Molecule Counting ...
We present a new approach to distinguish between non-ergodic and ergodic behavior. Performing ensemble averaging in a subpopulation of individual mol ...
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Bacterial Infections of the Cen ...
While bacterial infections of the central nervous system (CNS) constitute a group of serious and often life threatening diseases, the pathophysiology ...
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Advantages of Multidetector CT ...
Cancer of the urinary bladder is one of the most common urothelial neoplasms. Conventional cystoscopy is the mainstay in the diagnosis of urinary bla ...
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Monoclonal Antibodies as Innova ...
Monoclonal antibodies (mAbs) comprise the majority of protein candidates currently in clinical development because of their versatility as therapeuti ...
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Pathogenesis of Type 1 Diabetes ...
Targeted pancreatic ..-cell destruction by activated immune cells is a hallmark of type 1 diabetes in human beings and rodents. Activated T-lymphocyt ...
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Microencapsulation of Vaccine A ...
Delivery of vaccine antigens that can trigger potent mucosal immune response is one of the effective strategies to overcome a wide array of infectiou ...
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The Database dbEST Correctly Pr ...
This study aims to test the predictive power of gene expression data derived from NIH’s database dbEST, which collects gene expression results from a ...
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Hepatocytes as Cytotoxic Effect ...
The liver is increasingly recognized as an immune competent organ wherein aberrant T cell responses to dietary or autoantigens are suppressed, thereb ...
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Engineering of Therapeutic Prot ...
Low cost and simplicity of cultivating bacteria make the E. coli expression system a preferable choice for production of therapeutic proteins both on ...
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Antigenic Peptide Vaccination: ...
Recent immunotherapy depends largely on understanding of the molecular interactions between T cell receptors (TCR) on cytotoxic T lymphocytes (CTL) a ...
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AIDS Vaccines and Reproductive ...
It may appear that problems of reproductive immunology have little in common with issues of treatment and prevention of AIDS. However, the certain as ...
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TLR3 Sensing of Viral Infection
Viral infection is detected by the innate immune system which mounts a rapid semi-selective defence involving inflammation and production of type 1 i ...
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Foamy Virus Vectors
Human foamy virus (HFV) is a retrovirus of the spumavirus family. We have constructed vectors based on HFV that encode neomycin phosphotransferase an ...
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Lipid-Specific Immune Responses ...
Mycobacteria are unique in that their thick cell wall contains a variety of lipid and glycolipid components that are critical for survival and virule ...
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