Hypermethylation of the progest ...
Most breast carcinomas that are estrogen receptor (ER) and progesterone receptor (PR) positive respond initially to an endocrine therapy, but over t ...
Trastuzumab-DM1 (T-DM1) retains ...
Trastuzumab (Herceptin) is currently used as a treatment for patients whose breast tumors overexpress HER2/ErbB2. Trastuzumab-DM1 (T-DM1, trastuzum ...
Gene expression profile predict ...
Prognosis of early beast cancer is heterogeneous. Today, no histoclinical or biological factor predictive for clinical outcome after adjuvant anthra ...
Distinct function of androgen r ...
Steroid receptor coactivators are important in regulating the function of the receptors in endocrine organ development and in cancers, including bre ...
Genomics, histopathology, and t ...
Efforts to improve recurrence risk stratification for breast cancer patients have increasingly focused on rapidly developing gene expression profili ...
Supraclavicular recurrence afte ...
The prognosis of ipsilateral supraclavicular lymph node recurrence after early breast cancer appears to be worse than for other loco-regional recurr ...
The association between two pol ...
Emerging evidence has shown that miRNAs participate in human carcinogenesis as tumor suppressors or oncogenes. Single nucleotide polymorphism (SNP) ...
Inhibition of aldehyde dehydrog ...
The majority of breast cancer deaths are because of ineffective treatment of metastatic disease. We previously identified a subpopulation of cells i ...
A diagnostic gene profile for m ...
Classification of breast cancer into molecular subtypes maybe important for the proper selection of therapy, as tumors with seemingly similar histop ...
LDH-A silencing suppresses brea ...
LDH-A, as the critical enzyme accounting for the transformation from pyruvate into lactate, has been demonstrated to be highly expressed in various ...
Immunohistochemically defined s ...
The aim of this study is to evaluate the outcome of occult breast cancer (OBC) in patients with axillary presentation overall and according to the i ...
LMTK3 expression in breast canc ...
Interactions between kinases and the estrogen receptor a (ERa) are thought to be a critical signaling pathway in the majority of human breast cancer ...
Management of locoregional recu ...
The locoregional recurrence of breast cancer is not a sign of distant metastases, and a substantial proportion of cases are cured by salvage therapy ...
Pure mucinous carcinoma with ax ...
Pure mucinous carcinoma of the male breast is an extremely uncommon malignant breast neoplasm and usually occurs at advanced age. It is characterize ...
IgG4-related sclerosing disease ...
IgG4-related sclerosing disease was first identified and defined in the twenty-first century. In this pathology, the serum IgG4 level increases and ...
High TIMM17A expression is asso ...
Background Mitochondrial dysfunction can be associated with genomic instability and has been implicated in the pathogenesis of several human maligna ...
Switching the Loaded Agent from ...
Purpose There is no consensus on switching anticancer agents loaded onto drug carriers in transcatheter arterial chemoembolization (TACE) for hepato ...
Galectin-3 expression: a useful ...
Objective Galectin-3 (Gal-3) is a glycan-binding protein highly expressed in several tumors, including brain neoplasms. This protein has been demons ...
Spinal dermal sinus and pseudo- ...
Background Occult spinal dysraphism (OSD) encompasses various conditions. A dermal sinus tract (DST) consists of a duct communicating to the skin wi ...
The oculomotor nerve: anatomic ...
Purpose Endoscopic third ventriculostomy (ETV) has become first-line treatment for obstructive hydrocephalus. Many complications have been described ...
Inheritance of nasal dermoid si ...
Purpose The purpose of this paper is to study the possible inheritance of nasal dermoid sinus cyst in the Finnish population. Methods A patient que ...
Hieronymus Brunschwig (c. 1450– ...
Introduction The objective of this paper to offer an overview of the life and contributions of Hieronymus Brunschwig (also known as Jerome of Brunsw ...
A Japanese case of proteinase 3 ...
A 74-year-old male without recent medical treatment visited our hospital complaining of fever and lack of appetite. Upon examination severe azotemia ...
Effects of metallic or transluc ...
This study evaluated the performance of composite restorations placed with two matrix and wedge systems 4 years after placement. In a split-mouth de ...
Effect of two X-ray tube voltag ...
This study evaluated the effect of two different tube voltages on clinicians’ ability to diagnose approximal carious lesions in digital radiographs. ...