New Developments in Pancreatic Cancer
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New Developments in Pancreatic ...
Pancreatic adenocarcinoma presents in an advanced stage and has a dismal prognosis. Extensive recent research efforts have provided us with greater ...
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Recent Advances in Functional A ...
Defecatory disorders are a common cause of chronic constipation and should be managed by biofeedback-guided pelvic floor retraining. While anorectal ...
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Ablative Therapies for Barrett’ ...
Barrett’s esophagus has gained increased clinical attention because of its association with esophageal adenocarcinoma, a cancer with increasing inci ...
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Early Management of Severe Acut ...
Significant literature on the management of acute severe acute pancreatitis has emerged in recent years. The new information ranges from data on new ...
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Mechanisms Underlying Visceral ...
Visceral hypersensitivity is currently considered a key pathophysiological mechanism involved in pain perception in large subgroups of patients with ...
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Current Approach to the Treatme ...
Achalasia is a primary esophagealmotility disorder characterized by aperistalsis and incomplete or absent relaxation of the lower esophageal sphinct ...
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Helicobacter pylori: Is it a Co ...
Helicobacter pylori represents a major infection in humans and is a leading cause of peptic ulceration, chronic active gastritis, and gastric intest ...
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Evaluation of Patients with Sus ...
Laryngopharyngeal reflux (LPR) is associated with symptoms of laryngeal irritation such as throat pain, cough, and voice change. Currently, the two ...
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Obesity and GERD: Pathophysiolo ...
Epidemiologic, endoscopic, and pathophysiologic studies document the relationship between obesity and gastroesophageal reflux disease (GERD). Increa ...
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Diagnostic Utility of DNA from ...
For several years, PCR-based detection of Aspergillus DNA has been considered a promising tool for the diagnosis of invasive aspergillosis, but its ...
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Azole Resistance in Aspergillus ...
Azole resistance in Aspergillus fumigatus isolates is increasingly reported in different nosologic contexts with variable prevalence in different co ...
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Diagnosis of Antifungal Drug Re ...
Several fungal species can cause mild to severe diseases in humans. Antifungal strategies have been made possible by the development of several drug ...
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Non–Culture-Based Methods for t ...
Given the limitations of current fungal diagnostics, the use of non–culture-based methods for the diagnosis of invasive candidiasis (IC) is highly w ...
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Antifungal Therapy in Pediatric ...
Invasive fungal infections still play a major role in morbidity and mortality in pediatric patients, especially in children undergoing therapy for a ...
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Update on Antifungal Drug Dosin ...
The prevention and treatment of invasive fungal infections can be compromised by antifungal agents that display unpredictable pharmacokinetics and s ...
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The Current Role of Posaconazol ...
Zygomycosis is an emerging fungal disease that is associated with considerable excess morbidity and mortality. Standard approaches to treatment incl ...
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Immunogenetic Variability Assoc ...
Fungal infections remain a serious clinical problem with a high disease and financial burden, especially among immunocompromised and critically ill ...
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Antifungal Dosing in Obesity: A ...
Obesity is becoming a global pandemic that is projected to increase significantly over the next few decades. Unfortunately, studies of drug dosing a ...
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Fluconazole-Resistant Candida: ...
The extensive use of fluconazole in the previous two decades has fostered the emergence of azole-resistant strains, including non-albicans species s ...
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Polymerase Chain Reaction (PCR) ...
Candidemia and other types of invasive candidiasis are associated with mortality rates as high as 40% despite antifungal therapy. In part, the poor ...
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Antifungal Dosing in Dialysis a ...
Appropriate dosing of antifungal drugs is crucial to achieving favorable outcomes in patients with invasive fungal infections. The use of various ty ...
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Can We Achieve Clinical Breakpo ...
The azoles are first-line agents for the treatment of aspergillosis. A number of recent studies have shown increasing rates of resistance in A. fumi ...
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Antifungal Pharmacokinetics and ...
Patients with burn injuries are at high risk of developing invasive fungal infections leading to increased morbidity and mortality. Burn patients un ...
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Definitions and Epidemiology of ...
Antifungal susceptibility testing of Candida against the echinocandin antifungal agents (anidulafungin [ANF], caspofungin [CSF], micafungin [MCF]) h ...
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Pros and Cons of Extrapolating ...
Both the incidence of invasive fungal infections and the number of antifungal agents available to clinicians have expanded significantly over the pa ...
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