Gli1 enhances migration and inv ...
Gli1 is an established oncogene and its expression in Estrogen Receptor (ER) a negative and triple negative breast cancers is predictive of a poor p ...
Loss of one Tgfbr2 allele in fi ...
Accumulation of fibroblasts is a phenomenon that significantly correlates with formation of aggressive cancers. While studies have shown that the TG ...
Improvements in population-base ...
We analysed population-based treatment and survival data of patients who presented with metastatic rectal cancer. All patients diagnosed with primar ...
Mena invasive (MenaINV) and Men ...
Mena, an actin regulatory protein, functions at the convergence of motility pathways that drive breast cancer cell invasion and migration in vivo. T ...
Dynamics of cancer cell subpopu ...
Intratumor heterogeneity—heterogeneity of cancer cells within a single tumor—is considered one of the most problematic factors of treatment. Genetic ...
The dietary flavonoid apigenin ...
There is accumulating evidence that secondary plant metabolites such as flavonoids may have anti-cancer properties, and yet the molecular pathways t ...
Expression and significance of ...
HER receptor family plays an important role in normal embryonic development and is involved in pathogenesis and progression of some types of cancer. ...
Paracrine-mediated osteoclastog ...
Although in the past little attention has been paid to the influence of osteosarcoma cells in osteoclast function, recent studies suggest a close re ...
Identification of annexin A1 as ...
Metastasis is the most common cause of death in lung cancer patients and is a major obstacle to the successful treatment. To discover novel metastas ...
Genetic factors in metastatic p ...
The greatest potential for improvement of outcome for patients with Cutaneous Malignant Melanoma lies in the prevention of systemic metastasis. Desp ...
Association of a common variant ...
Diabetes is one of the most common and challenging health problems. Studies in several nations show that polymorphisms within the transcription fact ...
Detection methods of ZAP-70 in ...
The clinical course of patients with chronic lymphocytic leukemia (CLL) is highly heterogeneous, with some patients experiencing rapid disease progr ...
The expression of cyclin G in n ...
To investigate the expression of cyclin G1, cyclin G2 in nasopharyngeal carcinoma (NPC) cell lines and its significance. The protein expression of c ...
Natural resistance to apoptosis ...
Defects in apoptotic machinery vary among individual cancer cells, and the efficacy of chemotherapy in killing cancer cells depends on the successfu ...
Enhancement of subchondral bone ...
To evaluate the effects of alendronate (ALN) on the subchondral bone quality and cartilage degeneration in the early phase of experimental model of ...
Glomerulonephritis with crescen ...
The aim of this study is to investigate the clinical and pathological features and outcome of glomerulonephritis with crescents among adult patients ...
Gene expression of O-GlcNAc cyc ...
O-GlcNAcylation is an abundant, dynamic, and inducible posttranslational modification in which single b-N-acetylglucosamine residues are attached by ...
Association between the STin2 V ...
The serotonergic system may be involved in smoking behavior since the intake of nicotine increases serotonin secretion in the CNS. Moreover, evidenc ...
Comparison between clinical sig ...
Gastric cancer (GC) is a second most common cause of cancer-related death and represents an inflammation- driven malignancy. It has been suggested t ...
Ventriculoperitoneal shunt malf ...
Introduction Malfunction of cerebrospinal shunts is common and is due to multiple etiologies ranging from obstruction due to infiltrated brain tissu ...
Macrocephaly in neurofibromatos ...
Purpose Optic pathway gliomas, which occur in 15–20% of paediatric patients with neurofibromatosis type 1, are the most common central nervous syste ...
Urgent surgery is needed when c ...
Purpose The phenomenon of cyst enlargement in terminal myelocystocele (TMC) patients has been mentioned in the literature. However, its clinical sig ...
MGMT promoter gene methylation ...
Purpose Promoter methylation of the O6-methylguanine- DNA-methyltransferase (MGMT) gene is widely recognized as an important predictive factor in th ...
Computed tomography-guided ster ...
Purpose The primary objective of this study was to report the results of author’s 18-year experience of diagnostic stereotactic biopsy procedures in ...
Hydrocephalus in toddlers: the ...
of hydrocephalus in toddlers in our setting in order to determine the proportion of those who could benefit from endoscopic third ventriculostomy (E ...