Nephrotic syndrome developing d ...
This report is the first to document minimal change nephrotic syndrome occurring during induction chemotherapy for childhood acute lymphoblastic leu ...
A case of atypical hemolytic ur ...
9-year-old boy with pallor and macrohematuria showed hemolytic anemia, thrombocytopenia and renal failure. There was no history of diarrhea and the ...
Methylprednisolone pulse therap ...
Background The long-term prognosis of immunoglobulin A nephropathy (IgAN) is reportedly poor. In Japan, tonsillectomy-steroid pulse therapy has freq ...
Environmental factors influenci ...
Background There have been few investigations into the effects of environmental factors on the outcome of end-stage renal disease. Methods We inves ...
Usefulness of 3-month protocol ...
Background Theoretically, an early protocol biopsy (PB) serves to detect subclinical rejection (SCR), allowing early treatment and prevention of acu ...
Effects of renal dysfunction on ...
Background This study investigated the relation between renal dysfunction and cardiovascular events in patients from the Challenge-DM Study (a large ...
The association of plasma prore ...
Background Circulating prorenin contributes to the pathogenesis of tissue damage leading to cardiovascular disease (CVD) in hypertension and diabeti ...
Primed monocytes: putative culp ...
Background End-stage renal disease patients are known to be in a state of chronic low-grade inflammation and to have high infection-related morbidit ...
Elevated serum levels of interl ...
Background Interleukin-18 (IL-18), a pro-inflammatory cytokine, is a predictor of cardiovascular and renal disease in diabetic patients. Postprandia ...
Risk of macrovascular disease s ...
Background Although a high prevalence of macrovascular disease (MVD) has been reported in patients with stage 3 chronic kidney disease (CKD), few st ...
Management of anemia in chronic ...
Background Anemia is a factor that affects the outcome of patients with chronic kidney disease (CKD); however, there are only a few reports on the m ...
CD28 superagonist-induced regul ...
Background Naturally occurring regulatory T cells (Treg) are essential for the prevention of autoimmunity and overshooting immune responses to patho ...
Association between single nucl ...
Background Sirtuin is a member of the nicotinamide adenine dinucleotide (NAD)-dependent deacetylases, and has been reported to play a pivotal role i ...
A simple model for predicting i ...
Background Human immunodeficiency virus (HIV)- infected individuals have concurrent risk factors for chronic kidney disease (CKD), but there are no ...
Aldosterone-induced kidney inju ...
Background Aldosterone induces inflammation and fibrosis in the kidney, while nuclear factor jB (NFjB) plays key roles in inflammation mediated by v ...
Steroids and azathioprine in th ...
Aim IgA nephropathy (IgAN) is a very common glomerulonephritis among young adults, but the best therapeutic approach has not been fully elucidated. ...
The association between renal t ...
Background Injury to renal tubules plays an important role in the development of various renal diseases; however, the prevalence and significance of ...
Cisplatin induces Sirt1 in asso ...
Background Sirt1, a mammalian homolog of silent information regulator 2 (Sir2), is the founding member of class III histone deacetylase (HDAC). Met ...
Glucocorticoid enhances hypoxia ...
Background Glucocorticoid (GC) treatment reportedly exaggerates renal fibrosis in progressive kidney diseases during which hypoxia occurs as an unav ...
Dual myeloperoxidase-antineutro ...
Background Both myeloperoxidase-associated antineutrophil cytoplasmic antibody (MPO-ANCA) and antiglomerular basement membrane antibody (anti-GBMAb) ...
Upregulation of calbindin D28k ...
Background The calcium (Ca)-activated potassium (K) channel is an alternative K-secretory pathway in the apical membranes of the distal nephrons of ...
Renal preservation effect of ub ...
Background The aim of this study was to evaluate the renal preservation effect of ubiquinol, the reduced form of coenzyme Q10 (CoQ10). Methods Thre ...
Clinical significance of tubula ...
Background Acute kidney injury (AKI) is a common complication in critically ill patients. Urinary excretion of liver-type fatty acid-binding protein ...
Growth factor Midkine is involv ...
Background Growth factor Midkine (MK), which expresses on endothelial cells and renal proximal tubules, has been implicated in inflammation-related ...
Antigen-binding abilities of an ...
Background Nephrin is an essential protein for maintaining the normal structure of podocyte foot processes and the glomerular filtration barrier. To ...