Indeterminacy in the WHO classi ...
The WHO classifications of tumors are the global standards of tumor diagnosis. In spite of the detailed descriptions of the histopathological featur ...
Indication of intraoperative im ...
Immunohistochemical staining is important for histological diagnosis of brain tumors; however, its intraoperative application has rarely been report ...
Infratentorial brain metastases ...
Three pediatric patients with infratentorial metastatic non-epithelial malignant brain tumors were successfully treated by radical surgical resectio ...
Primary central nervous system ...
A 37-year-old man, a hepatitis B virus carrier due to mother-to-child transmission, had a medical examination in September 2008 in nearby hospitals ...
Metabolic assessment of monofoc ...
Monofocal acute inflammatory demyelination (MAID), which is observable by CT and MRI as a wellenhanced mass lesion with prominent perifocal edema, i ...
Pineal mixed germ cell tumor wi ...
Intracranial germ cell tumors (GCTs) typically affect children and adolescents. We here report on a 59-year-old male patient presenting with diplopi ...
Histopathological study of spin ...
Although the histogenesis of meningiomas remains unclear, it is believed that arachnoid cells are the most likely origin of this type of neoplasm. F ...
Brain metastases exhibit gross ...
Candidate genes involved in metastasis to the brain require investigation. In the present study, the adenomatous polyposis coli (APC) gene was analy ...
Olig2 is useful in the differen ...
A 42-year-old woman had suffered from headaches since April 2009. Computed tomography revealed a tumor with marked calcification in the left frontal ...
A case of atypical teratoid/rha ...
Atypical teratoid/rhabdoid tumor (AT/RT) is a malignant tumor that mostly occurs in early childhood and has poor prognosis despite aggressive therap ...
Clinicopathological and immunoh ...
The aim of this study was to summarize the clinicopathological features and the histological diversity of choroid plexus tumors and to examine the e ...
Spontaneous regression of multi ...
We present a case of spontaneous regression of multicentric pilocytic astrocytoma with cerebrospinal fluid (CSF) dissemination without neurofibromat ...
Rhabdoid glioblastoma in a chil ...
Rhabdoid glioblastoma is a rare type of glioblastoma characterized by cells resembling rhabdomyoblasts. Several reports have identified its aggressi ...
A miR-21 inhibitor enhances apo ...
MicroRNAs (miRNAs) are small noncoding RNAs that take part in diverse biological processes by suppressing target gene expression. Elevated expressio ...
Epstein–Barr virus (EBV)-associ ...
The frequency and clinical features of Epstein– Barr virus (EBV)-associated primary central nervous system lymphoma (PCNSL) in elderly patients were ...
Epithelioid glioblastoma change ...
A 55-year-old man was admitted to our hospital complaining of left hemiparesis. Magnetic resonance imaging (MRI) showed a smooth ring-like enhanced ...
New insights into glioma classi ...
In glioma, mutations in the isocitrate dehydrogenase 1 and 2 (IDH1/2) genes have been receiving attention. IDH1/2 mutations are frequently found in ...
Quantitative analysis of matrix ...
Malignant gliomas are characterized by their invasiveness and angiogenesis. Matrix metalloproteinases (MMPs) degrade extracellular matrix and create ...
Subependymal giant cell astrocy ...
A 49-year-old woman presented with a history of periodic episodes of nausea and vomiting starting in 2006. In June 2009, the patient lost consciousn ...
Non-promoter hypermethylation o ...
Zygote arrest 1 (ZAR1) is a novel maternal-effect gene of crucial importance during the oocyte-to-embryo transition. Comprehensive methylation analy ...
O6-Methylguanine DNA methyltran ...
Expression of the O6-methylguanine-DNA methyltransferase (MGMT) gene has been shown to correlate with clinical outcomes in patients with glioblastom ...
Precise comparison of protoporp ...
Photodynamic diagnosis is used during glioma surgery. Although some studies have shown that the spectrum of fluorescence was efficient for precise t ...
Persistent roles of signal tran ...
We previously reported that retrovirally transduced platelet-derived growth factor-B (PDGFB) in glial progenitors of the rat cerebral white matter, ...
Loss of heterozygosity analysis ...
Despite recent advances in the diagnosis and treatment of glioblastomas, patient outcomes for these highly malignant tumors remain poor. Research in ...
Detection of IDH1 mutation in h ...
Isocitrate dehydrogenase 1 (IDH1) mutations have recently been identified as early and frequent genetic alterations in astrocytomas, oligodendroglio ...