Proteome Analysis to Assess Phy ...
Proteome analysis was used to compare global protein expression changes in Escherichia coli fermentation between exponential and glucose-limited fed ...
Pre-hospital management of burn ...
Objective: To determine the current policies and practice of UK fire services for the management of burns patients. Methods: Structured telephone qu ...
Designing All-Hazards Incident ...
In this presentation, current emergency response practice in Japan will be reviewed in comparison with Incident Command System, which has been the de ...
Gene therapy for spinal fusion
Spinal fusion will continue to be an important part of the surgical treatment of spinal pathology for the foreseeable future. Traditional challenges ...
PowerMarker: an integrated anal ...
Summary: PowerMarker delivers a data-driven, integrated analysis environment (IAE) for genetic data. The IAE integrates data management, analysis an ...
Recombinant DNA expression prod ...
Recombinant DNA (rDNA) technology has made a revolutionary impact in the area of human healthcare by enabling mass production of safe, pure and effec ...
Biopharmaceuticals, expression ...
Recombinant DNA (rDNA) technology has made a revolutionary impact in the area of human healthcare by enabling mass production of safe, pure and effec ...
Cell cycle-dependent nuclear re ...
We show here that the cell cycle-dependent DNA-binding and transcriptional activity of p53 correlates with E2F expression in human primary fibroblas ...
Gene finding in the chicken gen ...
Background: Despite the continuous production of genome sequence for a number of organisms, reliable, comprehensive, and cost effective gene predicti ...
Haploview: analysis and visuali ...
Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particula ...
Exosomes: Specific Intercellula ...
The term “exosome” was coined in 1981 (Trams et al, Biochim Biophys Acta, 1981, 645:63) when the presence of “exfoliated membrane vesicles with 5’-nu ...
Mitochondrial Signal Transducti ...
Engagement of T cell receptors by antigen-presenting cells or stimulation by cytokines determine whether the cell will become activated, anergic or d ...
Lipid-Based Membrane Microdomai ...
The immune system is able to mount an immune response against antigens present in the body at very low concentrations and, at the same time, to discr ...
The Double Identity of WSX-1 (I ...
Two heterodimeric cytokines, IL-23 and IL-27, were recently identified, which have structural and functional homology to IL-12. IL-27, composed of p2 ...
Peripheral Tolerization of Effe ...
Due to the random generation of T cell antigen receptors, a large fraction of developing T cells have the potential to recognize self-determinants. T ...
Toll-Like Receptor Signaling: E ...
The family of Toll-like receptors (TLR1-TLR11) provides host defense in mammals by inducing proinflammatory innate immune response upon recognition o ...
Combating Bacterial Pathogens T ...
Antibiotic resistance, bioterrorism and microbial induced autoimmune disorders have made bacterial infections a growing concern in our society. To co ...
Innate Immunity in the Skin: Ho ...
The human skin is constantly exposed to a large number of external pathogens, due to the daily contact with the environment. The observation that ext ...
Activation and Costimulation of ...
T cells are present in large numbers in the epithelial lining of the small and large intestine of humans and mice. Those cells, referred to as intrae ...
Programmable DNA Binding Oligom ...
Mapping and sequencing the genetic blueprint in human, mice, yeast and other model organisms has created challenges and opportunities for chemistry, ...
Involvement of Nuclear Export i ...
The E6 protein from high-risk human papillomaviruses (HPVs) targets the p53 tumor suppressor for degradation by the proteasome pathway. This ability ...
The C Terminus of p53 Family Pr ...
The p53 tumor suppressor is the most commonly mutated gene in human cancers. The ability of p53 to induce cell cycle arrest, apoptosis, DNA repair, a ...
Modulation of p53 activity by I ...
Background: In this work we present evidence that the p53 tumor suppressor protein and NF-êB transcription factors could be related through common de ...
Reducing the Glucose Uptake Rat ...
Although glucose is an inexpensive substrate widely used as a carbon source in Escherichia coli recombinant fermentation technology, 10–30% of the ...
Modelling nutrient transport in ...
Recent experimental studies suggest that hollow fibre membrane bioreactors (HFMBs) may be used to grow three-dimensional (3D) bone tissue, which may ...