Primary Mediastinal Large B-Cell Lymphoma, Classic Hodg ...
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Primary Mediastinal Large B-Cel ...
In recent years, an overlap in biologic and clinical features has been identified between classic Hodgkin lymphoma (CHL) and primary mediastinal lar ...
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Chronic Myelogenous Leukemia: M ...
Molecular monitoring is a key component of the management of patients with chronic myeloid leukemia. The current recommendation is that molecular mo ...
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The Unique Characteristics and ...
In recent decades, the prognosis of Hodgkin lymphoma has been substantially improved, but these successes have been restricted to younger patients a ...
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Therapeutic Modalities for Pati ...
The treatment of myelodysplastic syndromes (MDS) involves a complex algorithm that depends on multiple factors, including symptoms, performance stat ...
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In Search of CML Stem Cells’ De ...
Chronic myeloid leukemia (CML) is a clonal myeloproliferative disorder that is characterized by the presence of a fusion oncogene, BCR-ABL, which en ...
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The Search for Better Prognosti ...
Myelodysplastic syndromes (MDS) are a group of heterogeneous bone marrow disorders characterized by a failure of hematopoiesis and an increased prop ...
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The Role of Autologous Transpla ...
Between 80% and 90% of Hodgkin lymphoma (HL) patients can be cured with up-to-date combinedmodality treatments, but patients with disease refractory ...
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Predicting the Response of CML ...
As of 2011, the choice of tyrosine kinase inhibitor (TKI) for the patient with newly diagnosed chronic-phase chronic myelogenous leukemia (CP-CML) ...
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Can Low-Risk, Early-Stage Patie ...
Advances in the treatment of Hodgkin lymphoma since about 1970 have led to a remarkable improvement in the long-term outcomes of what was once cons ...
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Future Therapies for the Myelop ...
Ever since their description as “myeloproliferative syndromes” by William Dameshek in 1951, the myeloproliferative neoplasms (MPNs) have been manage ...
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New Drugs for Chronic Myelogeno ...
The introduction of tyrosine kinase inhibitors (TKIs) has changed the landscape of therapy for chronic myelogenous leukemia (CML). Once considered a ...
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Treatment of Newly Diagnosed Mu ...
Treatment of myeloma has changed significantly in the past decade as a result of better understanding of disease biology, more effective treatments, ...
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Role of Tyrosine Kinase Inhibit ...
The Philadelphia chromosome is the most common cytogenetic abnormality found in adult patients diagnosed with acute lymphoblastic leukemia. The resu ...
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Special Issues in Myeloprolifer ...
Special issues in myeloproliferative neoplasms (MPN) comprise clinical conditions with high relevance for the duration and quality of the patient’s ...
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Treatment of Newly Diagnosed My ...
Melphalan plus prednisone (MP) has long been considered the gold-standard treatment for elderly patients with newly diagnosed myeloma, and it still ...
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Late Effects of Childhood Leuke ...
As survival rates for children treated for childhood cancers become significantly better, the focus is increasingly on determining the late effects ...
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What is the Best Frontline Ther ...
Chronic lymphocytic leukemia (CLL) is a lymphoproliferative disease with significant variation in disease progression, response to therapy, and surv ...
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New Immunomodulatory Drugs in M ...
Multiple myeloma (MM) is an incurable malignancy of plasma cells. The introduction of thalidomide was a milestone in the treatment of MM. Thalidomid ...
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The Role of Transplantation in ...
Rituximab has improved the prognosis of patients with diffuse large B-cell lymphoma, but a high proportion of patients with advanced disease will re ...
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Updates in Cytogenetics and Mol ...
Myelodysplastic syndromes (MDS) are clonal hematologic neoplasms that can result in cytopenias and increase the risk of leukemic transformation. The ...
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Burkitt Lymphoma and Atypical B ...
Burkitt lymphoma (BL) is a mature B-cell non- Hodgkin lymphoma with an aggressive clinical course. Since the advent of short, intensive, multiagent ...
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The Relevance of Iron Overload ...
Accumulation of excessive amounts of iron in vulnerable organs and tissues, together with elevated plasma and intracellular concentrations of reacti ...
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The Emerging Role of Histone De ...
T-cell lymphomas are an uncommon and heterogeneous group of non-Hodgkin lymphomas. Historically, therapies for these diseases have been borrowed fro ...
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Management of Lower-Risk Myelod ...
Myelodysplastic syndromes (MDS) represent a spectrum of bone marrow failure with variable outcome. Patients with “lower-risk” disease have an expect ...
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IL28B: Implications for Therapy
Within the last 2 years, a number of Genome- Wide Association Studies (GWAS) have shown that single nucleotide polymorphisms (SNPs) in the interleuk ...
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