Evidence for Enhanced Cytoprote ...
Background In the clinical field, increasing incidence of small intestinal ulcers associated with nonsteroidal antiinflammatory drugs (NSAIDs) has b ...
p53 Status and Its Prognostic R ...
The dysfunction of p53 is the most common genetic alteration in human cancer. A variety of studies have investigated the clinicopathologic correlati ...
p53 Status and Its Prognostic R ...
The dysfunction of p53 is the most common genetic alteration in human cancer. A variety of studies have investigated the clinicopathologic correlati ...
Beneficial Effects of Follistat ...
Background Ischemia-reperfusion injury has been demonstrated in a variety of clinical settings. The morbidity associated with liver transplantation ...
Antibiotic Prophylaxis Prevents ...
Background A recent post-infectious rat model with Campylobacter jejuni 81-176 has replicated the events noted in humans with post-infectious irrita ...
Mitochondrial Dependent Apoptos ...
Objectives Ischemia–reperfusion is a major event for induction of cellular apoptosis. Apoptosis is due to the activation of death receptor and/or mi ...
Pyloric Resection and Delayed G ...
Background Surgical resection of the distal stomach impairs gastric emptying. Generally, pylorus and the antrum are removed in the distal gastrectom ...
Preoperative Biliary Drainage B ...
Background The value of preoperative biliary drainage (PBD) before resection for hilar cholangiocarcinoma (HCCA) is still controversial nowadays. Th ...
Pioglitazone: A Promising Thera ...
Background Studies suggest that peroxisome proliferator- activated receptor c(PPARc) ligands may represent a therapeutic option in acute pancreatiti ...
Establishment of a Reflux Esoph ...
Background To investigate the pathophysiology of reflux laryngitis, an experimental model is required. Aim The aim of this study is to establish an ...
Myenteric Denervation Downregul ...
Background This study evaluated the galectin-1 and -3 expression during N-methyl-N0-nitro-N-nitrosoguanidine (MNNG)-induced gastric carcinogenesis i ...
The Esophageal Multimodal Pain ...
Background Sensory changes are thought to be involved in gastro-esophageal reflux disease (GERD). The esophageal multimodal pain model can be used t ...
Intragastrically Administered L ...
Background and Aim Lysophosphatidic acid exerts important physiological effects on many types of animal cells through its specific binding to severa ...
Role of Capsaicin-Sensitive Pri ...
Background Amifostine has been widely tested as a cytoprotective agent against a number of aggressors in different organs. Recently, a gastroprotect ...
Characterization of Expression ...
Background and Aim The regulation of human intestinal lactase-phlorizin hydrolase remains incompletely understood. One kb of pig and 2 kb of rat 50- ...
Expression and Prognostic Signi ...
Background CD151, c-Met, and integrin alpha3/alpha6 are all involved in the hepatocyte growth factor (HGF)/ c-Met signal pathway, which plays an imp ...
Rabeprazole Impedes the Develop ...
Background The role of proton pump inhibitors in Barrett’s metaplasia and esophageal adenocarcinoma has been an area of controversy. Aims We evalua ...
Increased Expression of Cellula ...
Background The cellular repressor of E1A-stimulated genes (CREG), a secreted glycoprotein, has been studied with human embryonic carcinoma cells, va ...
Poorly Treated or Unrecognized ...
Background The effect of gastroesophageal reflux disease (GERD) on health-related quality of life (HRQL) in COPD has never been assessed. Aim To ev ...
Effects of Ischemia and Reperfu ...
Purpose We investigated the effects of ischemia/reperfusion in the intestine (I/R-i) on purine receptor P2X2- immunoreactive (IR) neurons of the rat ...
Targeting PI3K/Akt/HSP90 Signal ...
Background The heat shock protein 90 (HSP90) plays a crucial role in the stability of several proteins that are essential for cell survival and for ...
Schistosoma mansoni Infection b ...
Background The ability of intestinal helminths tomanipulate the immune system of their host towards a Th2 response has been proposed to modulate aut ...
Reflux Parameters as Modified b ...
Background Patients with typical reflux symptoms (heartburn/ regurgitation) persisting despite proton pump inhibitor (PPI) therapy are not uncommon. ...
Mutational Analysis of the PTEN ...
Background Esophageal squamous cell carcinoma (ESCC) is one of the most frequently diagnosed cancers in China, but the etiology and mode of carcinog ...
Mechanism of Regulation of Na-H ...
Objective We investigated the role of toll-like receptor-4 (TLR-4) signal transduction in the regulation of Na-H exchanger-1 isoform (NHE-1) in ulce ...