Pros and Cons of Extrapolating ...
Both the incidence of invasive fungal infections and the number of antifungal agents available to clinicians have expanded significantly over the pa ...
Definitions and Epidemiology of ...
Antifungal susceptibility testing of Candida against the echinocandin antifungal agents (anidulafungin [ANF], caspofungin [CSF], micafungin [MCF]) h ...
Invasive Candidiasis in Patient ...
Implantable device infections are an important cause of invasive candidiasis and carry high rates of morbidity and mortality. Central vascular acces ...
Antifungal Pharmacokinetics and ...
Patients with burn injuries are at high risk of developing invasive fungal infections leading to increased morbidity and mortality. Burn patients un ...
Can We Achieve Clinical Breakpo ...
The azoles are first-line agents for the treatment of aspergillosis. A number of recent studies have shown increasing rates of resistance in A. fumi ...
Malassezia Species: A Rare Caus ...
The members of Malassezia species, which may cause skin disorders in healthy individuals, are associated with both cutaneous and systemic disorders ...
Antifungal Dosing in Dialysis a ...
Appropriate dosing of antifungal drugs is crucial to achieving favorable outcomes in patients with invasive fungal infections. The use of various ty ...
Polymerase Chain Reaction (PCR) ...
Candidemia and other types of invasive candidiasis are associated with mortality rates as high as 40% despite antifungal therapy. In part, the poor ...
Fluconazole-Resistant Candida: ...
The extensive use of fluconazole in the previous two decades has fostered the emergence of azole-resistant strains, including non-albicans species s ...
Antifungal Dosing in Obesity: A ...
Obesity is becoming a global pandemic that is projected to increase significantly over the next few decades. Unfortunately, studies of drug dosing a ...
Immunogenetic Variability Assoc ...
Fungal infections remain a serious clinical problem with a high disease and financial burden, especially among immunocompromised and critically ill ...
The Current Role of Posaconazol ...
Zygomycosis is an emerging fungal disease that is associated with considerable excess morbidity and mortality. Standard approaches to treatment incl ...
Update on Antifungal Drug Dosin ...
The prevention and treatment of invasive fungal infections can be compromised by antifungal agents that display unpredictable pharmacokinetics and s ...
Antifungal Therapy in Pediatric ...
Invasive fungal infections still play a major role in morbidity and mortality in pediatric patients, especially in children undergoing therapy for a ...
Non–Culture-Based Methods for t ...
Given the limitations of current fungal diagnostics, the use of non–culture-based methods for the diagnosis of invasive candidiasis (IC) is highly w ...
Invasive Candidiasis in the Neu ...
Invasive candidiasis (IC) is an important complication among cancer patients with neutropenia, as it is associated with significant mortality. Despi ...
Diagnosis of Antifungal Drug Re ...
Several fungal species can cause mild to severe diseases in humans. Antifungal strategies have been made possible by the development of several drug ...
Sporotrichosis Treatment: Overv ...
Sporotrichosis, caused by several species from the genus Sporothrix, mainly affects men working in agricultural labor. It is reported mostly from en ...
Azole Resistance in Aspergillus ...
Azole resistance in Aspergillus fumigatus isolates is increasingly reported in different nosologic contexts with variable prevalence in different co ...
Candidemia in the Pediatric Int ...
Candida species bloodstream infections have been associated with high morbidity and mortality, especially in patients hospitalized in a pediatric in ...
Diagnostic Utility of DNA from ...
For several years, PCR-based detection of Aspergillus DNA has been considered a promising tool for the diagnosis of invasive aspergillosis, but its ...
Obesity and GERD: Pathophysiolo ...
Epidemiologic, endoscopic, and pathophysiologic studies document the relationship between obesity and gastroesophageal reflux disease (GERD). Increa ...
Evaluation of Patients with Sus ...
Laryngopharyngeal reflux (LPR) is associated with symptoms of laryngeal irritation such as throat pain, cough, and voice change. Currently, the two ...
Helicobacter pylori: Is it a Co ...
Helicobacter pylori represents a major infection in humans and is a leading cause of peptic ulceration, chronic active gastritis, and gastric intest ...
Primary Prevention of Variceal ...
Variceal hemorrhage is one of the leading causes of death in patients with cirrhosis, with the 6-weekmortality after each episode ranging from 15% t ...